⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165354 | 0.71 | — | — | |
| SCHEMBL5165359 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL5167938 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL5167943 | 0.69 | — | — | |
| Trifluoroacetic Acid SCHEMBL18397163 | 0.67 | NOS1 (0.36) | — | |
| SCHEMBL16587957 | 0.67 | — | — | |
| SCHEMBL5185652 | 0.63 | — | — | |
| SCHEMBL477922 | 0.62 | — | — | |
| SCHEMBL17392903 | 0.62 | — | — | |
| SCHEMBL15200868 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037641-B2 | Modified nucleotide reagents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-20230366018-A1 | LABELED NUCLEOTIDE ANALOGS, REACTION MIXTURES, AND METHODS AND SYSTEMS FOR SEQUENCING | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-11-16 | — | — | US | disclosed |
| US-20230192749-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| US-20170321268-A1 | MODIFIED NUCLEOTIDE REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-11-09 | — | — | US | disclosed |
| US-20170145502-A1 | MODIFIED NUCLEOTIDE REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-05-25 | — | — | US | disclosed |
| US-20170145495-A1 | PROTECTED DYE-LABELED REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-05-25 | — | — | US | disclosed |
| US-20170145496-A1 | LABELED NUCLEOTIDE ANALOGS, REACTION MIXTURES, AND METHODS AND SYSTEMS FOR SEQUENCING | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-05-25 | — | — | US | disclosed |
| US-20160237279-A1 | MULTIMERIC PROTECTED FLUORESCENT REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-08-18 | — | — | US | disclosed |
| US-20150050659-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2015-02-19 | — | — | US | disclosed |