Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3673395 | 0.90 | SCD (0.43) | SCDFOLH1P2RY12SMN1; SMN2KDM4E | |
| SCHEMBL3669499 | 0.88 | SCD (0.44) | SCDFOLH1P2RY12SMN1; SMN2KDM4E | |
| SCHEMBL3670572 | 0.87 | SCD (0.47) | SCDNAMPTFOLH1P2RY12SMN1; SMN2 | |
| SCHEMBL3671024 | 0.87 | SCD (0.47) | SCDNAMPTFOLH1P2RY12SMN1; SMN2 | |
| SCHEMBL3668366 | 0.81 | SCD (0.43) | SCDNAMPTFOLH1P2RY12SMN1; SMN2 | |
| SCHEMBL3667718 | 0.79 | SCD (0.61) | SCDNAMPTFOLH1P2RY12SMN1; SMN2 | |
| SCHEMBL3675936 | 0.79 | HPGD (0.47) | SCDNAMPTFOLH1P2RY12SMN1; SMN2 | |
| SCHEMBL3669106 | 0.77 | SCD (0.49) | SCDNAMPTFOLH1P2RY12SMN1; SMN2 | |
| SCHEMBL3671047 | 0.77 | ME2 (0.46) | SCDFOLH1P2RY12USP30ALDH1A1 | |
| SCHEMBL3667701 | 0.77 | ME2 (0.46) | SCDNAMPTFOLH1P2RY12SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763350-B1 | NICOTINAMIDE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2011-12-21 | — | — | EP | claimed |