Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | CDC25B | P30305 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CDC25A | P30304 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL515789 | 1.00 | IDO1 (0.50) | IDO1MAPTLMNACDC25BALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL515791 | 1.00 | IDO1 (0.50) | IDO1MAPTLMNACDC25BALDH1A1 | |
| SCHEMBL515790 | 0.99 | IDO1 (0.51) | IDO1MAPTLMNACDC25BALDH1A1 | |
| SCHEMBL921265 | 0.69 | MAPK8 (0.65) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2920560 | 0.69 | IDO1 (0.66) | IDO1MAPTLMNACDC25BALDH1A1 | |
| SCHEMBL2952582 | 0.69 | IDO1 (0.66) | IDO1MAPTLMNACDC25BALDH1A1 | |
| SCHEMBL1670652 | 0.67 | IDO1 (1.00) | IDO1MAPTLMNACDC25BALDH1A1 | |
| SCHEMBL14764984 | 0.66 | KDM4E (0.60) | MAPTLMNACDC25BALDH1A1MEN1 | |
| SCHEMBL7146635 | 0.66 | CDC25B (0.68) | IDO1MAPTLMNACDC25BALDH1A1 | |
| SCHEMBL7140356 | 0.66 | CDC25B (0.68) | IDO1MAPTLMNACDC25BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |