SCHEMBL515790

SCHEMBL515790

CC1=C/C(=N\OCC(=O)O)c2ccccc2C1=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.51
MAPT P10636 8/20 0.44
LMNA P02545 6/20 0.44
CDC25B P30305 5/20 0.44
ALDH1A1 P00352 5/20 0.44
MEN1 O00255 3/20 0.44
BLM P54132 3/20 0.44
KMT2A Q03164 3/20 0.44
HPGD P15428 3/20 0.44
CDC25A P30304 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2D6 P10635 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
ATM Q13315 2/20 0.44
HIF1A Q16665 2/20 0.44
PLIN1 O60240 1/20 0.44
NR1I2 O75469 1/20 0.44
USP2 O75604 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL515791 0.99 IDO1 (0.50) IDO1MAPTLMNACDC25BALDH1A1
Ammonia Solution, Strong SCHEMBL515789 0.99 IDO1 (0.50) IDO1MAPTLMNACDC25BALDH1A1
Ammonia Solution, Strong SCHEMBL1649425 0.99 IDO1 (0.50) IDO1MAPTLMNACDC25BALDH1A1
SCHEMBL921265 0.70 MAPK8 (0.65) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL2952582 0.70 IDO1 (0.66) IDO1MAPTLMNACDC25BALDH1A1
SCHEMBL2920560 0.70 IDO1 (0.66) IDO1MAPTLMNACDC25BALDH1A1
SCHEMBL1670652 0.68 IDO1 (1.00) IDO1MAPTLMNACDC25BALDH1A1
SCHEMBL14764984 0.67 KDM4E (0.60) MAPTLMNACDC25BALDH1A1MEN1
SCHEMBL7146635 0.66 CDC25B (0.68) IDO1MAPTLMNACDC25BALDH1A1
SCHEMBL7140356 0.66 CDC25B (0.68) IDO1MAPTLMNACDC25BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 483 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11903992-B2 Composition comprising lidocaine, l-carnosine and dexpanthenol CELLIX BIO PRIVATE LIMITED (IN) 2024-02-20 US claimed
WO-2022157587-A1 A COMPOSITION COMPRISING LIDOCAINE, L-CARNOSINE AND DEXPANTHENOL CELLIX BIO PRIVATE LIMITED (IN) 2022-07-28 WO claimed
US-20220233629-A1 COMPOSITION COMPRISING LIDOCAINE, L-CARNOSINE AND DEXPANTHENOL CELLIX BIO PRIVATE LIMITED (IN) 2022-07-28 US claimed
US-9212214-B2 Methods of increasing the expression yield of vitamin K-dependent proteins CSL LIMITED (AU) 2015-12-15 US claimed
US-20150328323-A1 Nitric Oxide Releasing Produgs of Therapeutic Agents SATYAM APPARAO (IN) 2015-11-19 US claimed
US-20150283290-A1 STERILIZED COMPOSITIONS OF CYANOACRYLATE MONOMERS AND NAPHTHOQUINONE 2,3-OXIDES ADHEZION BIOMEDICAL, LLC (US) 2015-10-08 US claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
WO-2014111957-A1 NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS SATYAM APPARAO (IN) 2014-07-24 WO claimed
US-20130261603-A1 TREATMENT OF ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH ANTI-PROLIFERATE AND ANTI-INFLAMMATORY DRUGS LUTONIX, INC. (US) 2013-10-03 US claimed
US-20130253475-A1 TREATMENT OF ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH ANTI-PROLIFERATE AND ANTI-INFLAMMATORY DRUGS LUTONIX, INC. (US) 2013-09-26 US claimed
WO-2008063581-A2 TREATMENT OF ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH ANTI-PROLIFERATE AND ANTI-INFLAMMATORY DRUGS LUTONIX, INC. (US) 2008-05-29 WO claimed
US-20080118544-A1 Such as a balloon catheter or a stent; a drug not enclosed in micelles or encapsulated in particles or controlled release carriers and an additive having hydrophobic and hydrophilic portions; improved pharmacokinetics and bioavailability LUTONIX, INC. 2008-05-22 US claimed
JP-2008510795-A 2008-04-10 JP claimed
CN-101039701-A Prodrugs and codrug comprising a biocleavable disulfide linker NICHOLAS PIRAMAL INDIA LTD (IN) 2007-09-19 CN claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
EP-1789091-A2 PRODRUGS CONTAINING NOVEL BIO-CLEAVABLE LINKERS Nicholas Piramal India Limited (IN) 2007-05-30 EP claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20060205674-A2 PRODRUGS CONTAINING NOVEL BIO-CLEAVABLE LINKERS NICHOLAS PIRAMAL INDIA LTD. (IN) 2006-09-14 US claimed
WO-2006027711-A2 PRODRUGS AND CODRUGS CONTAINING BIO- CLEAVABLE DISULFIDE LINKERS NICHOLAS PIRAMAL INDIA LIMITED (IN) 2006-03-16 WO claimed
US-20060046967-A1 Prodrugs containing novel bio-cleavable linkers Piramal Enterprises Limited (IN) 2006-03-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11903992-B2 Composition comprising lidocaine, l-carnosine and dexpanthenol VNN1, LPL, HMGB1 IDO1 2692/4885MAPT 3934/4885LMNA 16/4885
US-20060046967-A1 Prodrugs containing novel bio-cleavable linkers SI, UGT1A1, CYP2B6 IDO1 818/4885MAPT 3055/4885LMNA 1990/4885
US-20150328323-A1 Nitric Oxide Releasing Produgs of Therapeutic Agents NOS2, NOS1, PTGIS IDO1 455/4885MAPT 3547/4885LMNA 1146/4885
US-20220233629-A1 COMPOSITION COMPRISING LIDOCAINE, L-CARNOSINE AND DEXPANTHENOL VNN1, LPL, HMGB1 IDO1 2692/4885MAPT 3934/4885LMNA 16/4885
US-20060205674-A2 PRODRUGS CONTAINING NOVEL BIO-CLEAVABLE LINKERS SI, UGT1A1, PAICS IDO1 600/4885MAPT 3198/4885LMNA 2549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.