Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 12/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16495182 | 0.89 | ACHE (0.58) | ACHE | |
| SCHEMBL16494086 | 0.87 | ACHE (0.68) | ACHE | |
| SCHEMBL16494219 | 0.86 | ACHE (0.62) | ACHE | |
| SCHEMBL16494639 | 0.86 | ACHE (0.62) | ACHEMEN1KMT2A | |
| SCHEMBL16494625 | 0.85 | ACHE (0.63) | ACHE | |
| SCHEMBL16494973 | 0.85 | ACHE (0.63) | ACHE | |
| SCHEMBL16495125 | 0.85 | ACHE (0.66) | ACHE | |
| SCHEMBL16494309 | 0.84 | ACHE (0.59) | ACHE | |
| SCHEMBL16494110 | 0.84 | ACHE (0.60) | ACHEMEN1KMT2A | |
| SCHEMBL16494217 | 0.84 | ACHE (0.59) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394990-A1 | INDOLINE DERIVATIVES | Kyoto University (JP) | 2011-12-14 | — | — | EP | disclosed |