Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 7/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | LDHA | P00338 | 1/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.57 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.57 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.57 |
| ▸ | PRKCG | P05129 | 1/20 | 0.57 |
| ▸ | PRKACA | P17612 | 1/20 | 0.57 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | AKT1 | P31749 | 1/20 | 0.57 |
| ▸ | GSK3A | P49840 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | PRKX | P51817 | 1/20 | 0.57 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.57 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16495576 | 0.91 | HPGDS (0.82) | HPGDSL3MBTL1BAZ2BALOX15ROCK2 | |
| SCHEMBL16495652 | 0.91 | HPGDS (0.82) | HPGDSL3MBTL1BAZ2BALOX15LDHA | |
| SCHEMBL16495596 | 0.91 | HPGDS (0.82) | HPGDSL3MBTL1BAZ2BLDHAHDAC2 | |
| SCHEMBL16496250 | 0.91 | HPGDS (0.82) | HPGDSL3MBTL1BAZ2BLDHAHDAC2 | |
| SCHEMBL16495963 | 0.88 | HPGDS (0.79) | HPGDSL3MBTL1BAZ2BALOX15LDHA | |
| SCHEMBL16495842 | 0.87 | HPGDS (0.77) | HPGDSL3MBTL1BAZ2BROCK2ROCK1 | |
| SCHEMBL16495795 | 0.87 | HPGDS (0.77) | HPGDSL3MBTL1BAZ2BALOX15LDHA | |
| SCHEMBL16495479 | 0.87 | HPGDS (0.77) | HPGDSL3MBTL1BAZ2BALOX15MAP4K4 | |
| SCHEMBL16495525 | 0.87 | HPGDS (0.77) | HPGDSL3MBTL1BAZ2BMMP13HDAC2 | |
| SCHEMBL16495630 | 0.87 | HPGDS (0.77) | HPGDSL3MBTL1BAZ2BALOX15MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110306597-A1 | Nicotinamide Derivatives | CRAWFORTH JAMES MICHAEL (GB) | 2011-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306597-A1 | Nicotinamide Derivatives | NNT, NAMPT, NQO1 | HPGDS 1073/4885L3MBTL1 4532/4885BAZ2B 1779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.