Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.55 |
| ▸ | MLNR | O43193 | 5/20 | 0.45 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16496171 | 0.93 | HPGDS (0.53) | HPGDSMLNRSRCDRD2DRD4 | |
| SCHEMBL16496076 | 0.92 | HPGDS (0.54) | HPGDSMLNRSRCDRD2DRD4 | |
| SCHEMBL16495774 | 0.89 | MCHR1 (0.45) | HPGDSMLNRSRCHDAC1HDAC8 | |
| SCHEMBL16495915 | 0.89 | SRC (0.51) | HPGDSSRCDRD2DRD4HDAC1 | |
| SCHEMBL16495485 | 0.84 | SRC (0.50) | HPGDSSRCDRD2DRD4HDAC1 | |
| SCHEMBL1364946 | 0.83 | DRD4 (0.43) | HPGDSSRCDRD2DRD4HDAC1 | |
| SCHEMBL2070489 | 0.83 | HPGDS (0.73) | HPGDSDRD2DRD4CCR2MCHR1 | |
| SCHEMBL16496114 | 0.83 | SSTR3 (0.45) | HPGDSMLNRSRCHDAC1HDAC8 | |
| SCHEMBL16496138 | 0.82 | SRC (0.49) | HPGDSSRCDRD2DRD4HDAC1 | |
| SCHEMBL16495584 | 0.81 | SRC (0.53) | HPGDSMLNRSRCHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110306597-A1 | Nicotinamide Derivatives | CRAWFORTH JAMES MICHAEL (GB) | 2011-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306597-A1 | Nicotinamide Derivatives | NNT, NAMPT, NQO1 | HPGDS 1073/4885MLNR 1678/4885SRC 4371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.