⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15894639 | 0.78 | — | — | |
| SCHEMBL7162393 | 0.69 | — | — | |
| SCHEMBL6202960 | 0.62 | — | — | |
| SCHEMBL18211729 | 0.59 | — | — | |
| SCHEMBL28184226 | 0.57 | — | — | |
| SCHEMBL28922596 | 0.55 | — | — | |
| Ethylamine SCHEMBL8646820 | 0.54 | — | — | |
| SCHEMBL19167321 | 0.53 | — | — | |
| SCHEMBL729112 | 0.52 | — | — | |
| SCHEMBL20921304 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115627629-A | Antifouling processing method for fishing net rope by using hydroxy acid ester oligomer compound antifouling agent and product thereof | 浙江英玛特生物科技有限公司 | 2023-01-20 | — | — | CN | claimed |
| CN-111837146-B | G1T38 excellent dosing regimen | G1治疗公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-118234496-A | Improved treatment of advanced/metastatic cancers with checkpoint inhibitor resistance or drug resistance susceptibility | 海南先声再明医药股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-118047687-A | Compound for modifying 20 (S) camptothecin structure and synthesis method thereof | 湖州澄博生物科技有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-117562905-A | Maintenance of immune response during chemotherapy regimen | G1治疗公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-117530948-A | Maintenance of immune response during chemotherapy regimen | G1治疗公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-113406327-B | Diagnosis and treatment of cancer involving cancer stem cells | 生物技术公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116437913-A | Pharmaceutical compounds for treating complement-mediated disorders | 艾其林医药公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-109172820-B | Combination therapy involving antibodies directed against claudin 18.2 for the treatment of cancer | 加尼梅德药物公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-115989040-A | Phospholipid-containing drug-clay mineral complex and orally administrable composition comprising same | 韩国地质资源研究院 | 2023-04-18 | — | — | CN | disclosed |
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |
| US-20100297214-A1 | PERCOLATIVE DRYING FOR THE PREPARATION OF PARTICLES | MEDIGENE AG (DE) | 2010-11-25 | — | — | US | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |
| CN-101478968-A | Camptothecin-analog with a novel, flipped lactone-stable, E-ring and methods for making and using same | BIONUMERIK PHARMACEUTICALS INC (US) | 2009-07-08 | — | — | CN | disclosed |
| EP-1915987-A1 | Spray-freeze-drying process for the preparation of pellets comprising percolation drying | MediGene AG (DE) | 2008-04-30 | — | — | EP | disclosed |
| CN-101106995-A | Pharmaceutical formulation for increasing solubility of 10-hydroxycamptothecin compounds in non-aqueous polar solvents | SAMYANG CORP (KR) | 2008-01-16 | — | — | CN | disclosed |
| CN-101007808-A | Process for preparing superfine camptothecine | UNIV BEIJING CHEMICAL (CN) | 2007-08-01 | — | — | CN | disclosed |
| EP-0555347-A4 | SUBSTITUTED INDOLIZINO 1,2-B)QUINOLINONES | SMITHKLINE BEECHAM CORP (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0555347-A1 | SUBSTITUTED INDOLIZINO 1,2-b]QUINOLINONES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-08-18 | — | — | EP | disclosed |
| WO-1992007856-A1 | SUBSTITUTED INDOLIZINO[1,2-b]QUINOLINONES | SMITHKLINE BEECHAM CORPORATION (US) | 1992-05-14 | — | — | WO | disclosed |