⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4942102 | 0.68 | — | — | |
| SCHEMBL20286444 | 0.65 | — | — | |
| SCHEMBL1649673 | 0.62 | — | — | |
| SCHEMBL15894639 | 0.51 | — | — | |
| SCHEMBL28184226 | 0.49 | — | — | |
| SCHEMBL3643512 | 0.46 | — | — | |
| SCHEMBL7866926 | 0.46 | — | — | |
| SCHEMBL729112 | 0.45 | — | — | |
| SCHEMBL18211729 | 0.45 | — | — | |
| SCHEMBL7162393 | 0.45 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1251125-B1 | New camptothecin analogues, preparation methods thereof, use thereof as drugs, and pharmaceutical compositions containing them | SOD CONSEILS RECH APPLIC (FR) | 2005-12-07 | — | — | EP | disclosed |
| CN-1227254-C | Pyridone compound and its prepn process | SOD CONSEILS RECH APPLIC (FR) | 2005-11-16 | — | — | CN | disclosed |
| EP-0946566-B1 | PRO-DRUGS AND COUNTERPARTS OF CAMPTOTHECIN, THEIR APPLICATION AS MEDICINES | SOD CONSEILS RECH APPLIC (FR) | 2003-11-05 | — | — | EP | disclosed |
| EP-0946567-B1 | NOVEL COUNTERPARTS OF CAMPTOTHECIN, THEIR APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SOD CONSEILS RECH APPLIC (FR) | 2003-08-27 | — | — | EP | disclosed |
| CN-1432571-A | Pyridone compound and its prepn process | SOD CONSEILS RECH APPLIC (FR) | 2003-07-30 | — | — | CN | disclosed |
| CN-1114608-C | Camptothecin analogue, preparation method thereof, pharmaceutical application and pharmaceutical composition thereof | SOD CONSEILS RECH APPLIC (FR) | 2003-07-16 | — | — | CN | disclosed |
| CN-1097056-C | Counterparts of camptothecin, their application as medicine and pharmaceutical compositions contg. them | CONSILS DE RECH S ET D APPLIC (FR) | 2002-12-25 | — | — | CN | disclosed |
| EP-1251125-A2 | New camptothecin analogues, preparation methods thereof, use thereof as drugs, and pharmaceutical compositions containing them | Société de Conseils et de Recherches d'Applications Scientifiques (S.C.R.A.S.) (FR) | 2002-10-23 | — | — | EP | disclosed |
| EP-0835258-B1 | NOVEL CAMPTOTHECIN ANALOGUES, PREPARATION METHODS THEREFOR, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID ANALOGUES | SOD CONSEILS RECH APPLIC (FR) | 2002-09-25 | — | — | EP | disclosed |
| CN-1090634-C | Pro-drugs and counterparts of camptothecin, their application as medicines | SOD CONSEILS RECH APPLIC (FR) | 2002-09-11 | — | — | CN | disclosed |
| CN-1241192-A | Pro-drugs and counterparts of camptothecin, their application as medicines | SOD CONSEILS RECH APPLIC (FR) | 2000-01-12 | — | — | CN | disclosed |
| CN-1241191-A | Novel analogues of camptothecin, their use as medicaments and pharmaceutical compositions containing them | SOD CONSEILS RECH APPLIC (FR) | 2000-01-12 | — | — | CN | disclosed |
| US-5981542-A | TOPOISOMERASE INHIBITORS; ANTITUMORAL DRUGS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1999-11-09 | — | — | US | disclosed |
| EP-0946566-A1 | PRO-DRUGS AND COUNTERPARTS OF CAMPTOTHECIN, THEIR APPLICATION AS MEDICINES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1999-10-06 | — | — | EP | disclosed |
| CN-1192740-A | Novel camptothecin analogues, their preparation method, their pharmaceutical use and their pharmaceutical compositions | SOD CONSEILS RECH APPLIC (FR) | 1998-09-09 | — | — | CN | disclosed |
| WO-1998028304-A1 | PRO-DRUGS AND COUNTERPARTS OF CAMPTOTHECIN, THEIR APPLICATION AS MEDICINES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-07-02 | — | — | WO | disclosed |