Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 11/20 | 0.56 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.56 |
| ▸ | FAP | Q12884 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4956097 | 0.83 | DPP7 (0.78) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL8852004 | 0.83 | DPP7 (0.78) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL2182868 | 0.83 | DPP7 (0.78) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL1648959 | 0.83 | OPRK1 (0.44) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2182923 | 0.80 | DPP4 (0.52) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL5050089 | 0.80 | DPP4 (0.52) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL6438877 | 0.80 | DPP4 (0.52) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL7172842 | 0.79 | DPP4 (0.56) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL13034923 | 0.78 | DPP4 (0.73) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL13783426 | 0.78 | DPP4 (0.73) | DPP4DPP7DPP8DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |