Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 15/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.45 |
| ▸ | CCKAR | P32238 | 10/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16498605 | 0.94 | CCKBR (0.48) | CCKBRLRRK2CCKAR | |
| SCHEMBL16498157 | 0.94 | CCKBR (0.52) | CCKBRLRRK2CCKAR | |
| SCHEMBL16498283 | 0.92 | CCKBR (0.49) | CCKBRCCKAR | |
| SCHEMBL16498178 | 0.92 | CCKBR (0.48) | CCKBRCCKAR | |
| SCHEMBL16498423 | 0.90 | CCKBR (0.51) | CCKBRCCKAR | |
| SCHEMBL16499162 | 0.89 | CCKBR (0.50) | CCKBRCCKAR | |
| SCHEMBL16498176 | 0.87 | CCKBR (0.48) | CCKBRCCKAR | |
| SCHEMBL1506007 | 0.87 | CCKBR (0.52) | CCKBRCCKAR | |
| SCHEMBL1506003 | 0.87 | CCKBR (0.52) | CCKBRCCKAR | |
| SCHEMBL1506002 | 0.87 | CCKBR (0.52) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151651-A1 | BENZODIAZEPINE COMPOUNDS USEFUL FOR THE TREATMENT OF HEPATITIS C | ARROW THERAPEUTICS LIMITED (GB) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151651-A1 | BENZODIAZEPINE COMPOUNDS USEFUL FOR THE TREATMENT OF HEPATITIS C | ARROW THERAPEUTICS LIMITED (GB) | 2011-12-08 | — | — | WO | disclosed |