Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 11/20 | 0.75 |
| ▸ | SLC12A5 | Q9H2X9 | 3/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16498154 | 1.00 | FFAR2 (0.75) | FFAR2SLC12A5CTSKALDH1A1TP53 | |
| SCHEMBL16498608 | 0.93 | FFAR2 (0.84) | FFAR2SLC12A5CTSKALDH1A1MMP2 | |
| SCHEMBL16498610 | 0.93 | FFAR2 (0.84) | FFAR2SLC12A5CTSKALDH1A1MMP2 | |
| SCHEMBL16498042 | 0.92 | FFAR2 (0.86) | FFAR2SLC12A5ALDH1A1TP53GAA | |
| SCHEMBL16498045 | 0.92 | FFAR2 (0.86) | FFAR2SLC12A5ALDH1A1TP53GAA | |
| SCHEMBL1915824 | 0.86 | FFAR2 (1.00) | FFAR2SLC12A5ALDH1A1MMP2MMP9 | |
| SCHEMBL1915829 | 0.86 | FFAR2 (1.00) | FFAR2SLC12A5ALDH1A1MMP2MMP9 | |
| SCHEMBL16498080 | 0.86 | FFAR2 (0.71) | FFAR2SLC12A5CTSKMMP2MMP9 | |
| SCHEMBL16498084 | 0.86 | FFAR2 (0.71) | FFAR2SLC12A5CTSKMMP2MMP9 | |
| SCHEMBL1915492 | 0.85 | FFAR2 (0.98) | FFAR2SLC12A5CTSKALDH1A1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151434-A1 | NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | claimed |
| WO-2011151434-A1 | NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | disclosed |