SCHEMBL16498196

SCHEMBL16498196

CN1C(=O)C(C)(C)c2cc(-c3ccccc3-c3csc(N(C(=O)C(CC(=O)O)CC4CCCC4)C4CC4)n3)cnc21

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 11/20 0.68
USP19 O94966 7/20 0.34
SLC12A5 Q9H2X9 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16498194 1.00 FFAR2 (0.68) FFAR2USP19SLC12A5
SCHEMBL1916231 0.87 FFAR2 (0.68) FFAR2USP19SLC12A5
SCHEMBL1916227 0.87 FFAR2 (0.68) FFAR2USP19SLC12A5
SCHEMBL16498232 0.86 FFAR2 (0.68) FFAR2USP19SLC12A5
SCHEMBL1917470 0.86 FFAR2 (0.68) FFAR2USP19SLC12A5
SCHEMBL1917466 0.86 FFAR2 (0.68) FFAR2USP19SLC12A5
SCHEMBL16498237 0.86 FFAR2 (0.68) FFAR2USP19SLC12A5
SCHEMBL16498579 0.85 FFAR2 (0.66) FFAR2USP19SLC12A5
SCHEMBL16498582 0.85 FFAR2 (0.66) FFAR2USP19SLC12A5
SCHEMBL1917095 0.85 FFAR2 (0.69) FFAR2USP19SLC12A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011151434-A1 NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS EUROSCREEN S.A. (BE) 2011-12-08 WO disclosed