Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11129614 | 0.85 | ABL1 (0.48) | MAPTABL1 | |
| SCHEMBL2796366 | 0.83 | MAPT (0.52) | MAPTABL1S1PR4HPGD | |
| SCHEMBL1154092 | 0.83 | KDM4E (0.54) | MAPTABL1S1PR4HPGD | |
| SCHEMBL3654708 | 0.83 | — | — | |
| SCHEMBL2799514 | 0.82 | MAPT (0.55) | MAPTABL1S1PR4HPGD | |
| SCHEMBL6421995 | 0.82 | SLC6A4 (0.51) | MAPTABL1S1PR4HPGD | |
| SCHEMBL4360418 | 0.82 | LMNA (0.51) | MAPTABL1S1PR4HPGD | |
| SCHEMBL1505120 | 0.82 | S1PR4 (0.52) | MAPTABL1S1PR4HPGD | |
| SCHEMBL929622 | 0.82 | MAPT (0.50) | MAPTABL1S1PR4HPGD | |
| Hydrochloric Acid SCHEMBL1505095 | 0.81 | MAPT (0.50) | MAPTABL1S1PR4HPGDNLRP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151651-A1 | BENZODIAZEPINE COMPOUNDS USEFUL FOR THE TREATMENT OF HEPATITIS C | ARROW THERAPEUTICS LIMITED (GB) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151651-A1 | BENZODIAZEPINE COMPOUNDS USEFUL FOR THE TREATMENT OF HEPATITIS C | ARROW THERAPEUTICS LIMITED (GB) | 2011-12-08 | — | — | WO | disclosed |