Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16499408 | 1.00 | HSP90AA1 (0.33) | HSP90AA1KDM4EMEN1USP2TP53 | |
| SCHEMBL12821645 | 1.00 | HSP90AA1 (0.33) | HSP90AA1KDM4EMEN1USP2TP53 | |
| SCHEMBL12821630 | 0.83 | — | — | |
| SCHEMBL12821419 | 0.82 | PDK2 (0.32) | USP2 | |
| SCHEMBL16499584 | 0.77 | ACHE (0.35) | HSP90AA1KDM4EMEN1USP2TP53 | |
| SCHEMBL16499433 | 0.77 | ACHE (0.35) | HSP90AA1KDM4EMEN1USP2TP53 | |
| SCHEMBL12821396 | 0.77 | ACHE (0.35) | HSP90AA1KDM4EMEN1USP2TP53 | |
| SCHEMBL12825568 | 0.66 | — | — | |
| SCHEMBL12825554 | 0.66 | — | — | |
| SCHEMBL5445033 | 0.66 | GRM1 (0.33) | KDM4EMEN1CYP3A4KMT2ANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011155983-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC. (US) | 2011-12-15 | — | — | WO | disclosed |