Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409270 | 0.75 | DYRK3 (0.43) | KDM4ENPC1GAAALK | |
| SCHEMBL27947333 | 0.64 | FGFR1 (0.43) | KDM4ENPC1GAA | |
| SCHEMBL16500231 | 0.64 | NPC1 (0.43) | HDAC1HDAC8HDAC6KDM4ENPC1 | |
| SCHEMBL699438 | 0.63 | MAP4K4 (0.36) | KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20412071 | 0.63 | PDE3B (0.46) | ALK | |
| SCHEMBL27847161 | 0.62 | PDPK1 (0.44) | — | |
| SCHEMBL1104828 | 0.62 | HDAC1 (0.64) | HDAC1HDAC8HDAC6NLRP3NAMPT | |
| SCHEMBL3103036 | 0.61 | NQO2 (0.43) | KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28013699 | 0.61 | KMT2A (0.58) | GAARAB9ASMN1; SMN2 | |
| SCHEMBL29062356 | 0.60 | KMT2A (0.41) | KDM4ECYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373631-B1 | ANTIBACTERIAL COMPOUNDS | SUMMIT CORP PLC (GB) | 2015-02-25 | — | — | EP | claimed |