SCHEMBL1104828

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16692131	0.94	HDAC1 (0.59)	HDAC1HDAC8HDAC6PDE10AATM
	SCHEMBL3752453	0.92	HDAC1 (0.57)	HDAC1HDAC8HDAC6PDE10AATM
	SCHEMBL13098078	0.91	HDAC1 (0.56)	HDAC1HDAC8HDAC6PDE10AATM
	SCHEMBL10030014	0.90	NLRP3 (0.61)	HDAC1HDAC8HDAC6PDE10AATM
	SCHEMBL9976962	0.89	HDAC1 (0.54)	HDAC1HDAC8HDAC6PDE10AATM
	SCHEMBL12912532	0.89	HDAC1 (0.53)	HDAC1HDAC8HDAC6PDE10AATM
	SCHEMBL13042818	0.89	HDAC1 (0.54)	HDAC1HDAC8HDAC6PDE10AATM
	SCHEMBL13043014	0.89	HDAC1 (0.54)	HDAC1HDAC8HDAC6PDE10AATM
	SCHEMBL1104827	0.88	PDE10A (0.59)	HDAC1HDAC8HDAC6PDE10AATM
	SCHEMBL10949479	0.88	CA1 (0.51)	HDAC1HDAC8HDAC6PDE10AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.