Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2266985 | 0.96 | KCNN4 (0.36) | RIPK1KCNN4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2266997 | 0.96 | KCNN4 (0.36) | RIPK1KCNN4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2266993 | 0.96 | KCNN4 (0.36) | RIPK1KCNN4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15969381 | 0.88 | RIPK1 (0.46) | RIPK1KCNN4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2266629 | 0.87 | RIPK1 (0.39) | RIPK1KCNN4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2266633 | 0.87 | RIPK1 (0.39) | RIPK1KCNN4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12366406 | 0.86 | HTR2C (0.40) | RIPK1HTR2CHTR2AHTR2B | |
| SCHEMBL2264815 | 0.86 | RIPK1 (0.40) | RIPK1KCNN4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2264820 | 0.86 | RIPK1 (0.40) | RIPK1KCNN4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12366353 | 0.83 | RIPK1 (0.40) | RIPK1KCNN4SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860089-B1 | DIFLUOROBENZENE DERIVATIVE AND NEMATIC LIQUID CRYSTAL COMPOSITION MAKING USE OF THE SAME | DAINIPPON INK & CHEMICALS (JP) | 2011-12-21 | — | — | EP | disclosed |