Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA6 | P08185 | 5/20 | 0.61 |
| ▸ | AR | P10275 | 6/20 | 0.59 |
| ▸ | PGR | P06401 | 5/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.50 |
| ▸ | SHBG | P04278 | 2/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23383533 | 1.00 | SERPINA6 (0.61) | SERPINA6ARPGRCYP3A4ALDH1A1 | |
| SCHEMBL2832958 | 0.85 | SHBG (0.59) | SERPINA6ARPGRCYP3A4ALDH1A1 | |
| SCHEMBL30140884 | 0.85 | SHBG (0.59) | SERPINA6ARPGRCYP3A4ALDH1A1 | |
| SCHEMBL7703808 | 0.85 | SHBG (0.59) | SERPINA6ARPGRCYP3A4ALDH1A1 | |
| SCHEMBL12101456 | 0.84 | CYP17A1 (0.54) | SERPINA6ARPGRCYP3A4ALDH1A1 | |
| SCHEMBL14200096 | 0.84 | CYP17A1 (0.54) | SERPINA6ARPGRCYP3A4ALDH1A1 | |
| SCHEMBL13397495 | 0.84 | CYP17A1 (0.54) | SERPINA6ARPGRCYP3A4ALDH1A1 | |
| SCHEMBL8843324 | 0.84 | CYP17A1 (0.54) | SERPINA6ARPGRCYP3A4ALDH1A1 | |
| SCHEMBL17302786 | 0.84 | CYP17A1 (0.54) | SERPINA6ARPGRCYP3A4ALDH1A1 | |
| SCHEMBL12437208 | 0.84 | CYP17A1 (0.54) | SERPINA6ARPGRCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |
| US-5703066-A | TREATING GYNECOLOGICAL DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-30 | — | — | US | disclosed |
| WO-1997027209-A1 | NEW SUBSTITUTED 19-NOR-PREGNANE DERIVATIVES | LABORATOIRE THERAMEX (MC) | 1997-07-31 | — | — | WO | disclosed |
| WO-1995011915-A1 | 10,11β-C2-BRIDGED STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-05-04 | — | — | WO | disclosed |
| US-4456601-A | ANTIINFLAMMATORY, ANTIPYRETICS AGENTS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-06-26 | — | — | US | disclosed |