Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 2/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16414460 | 0.79 | MMP12 (0.38) | TSHRMMP12PRSS1CTSGCTRB1 | |
| SCHEMBL16414506 | 0.79 | MMP12 (0.38) | TSHRMMP12PRSS1CTSGCTRB1 | |
| SCHEMBL16414459 | 0.79 | MMP12 (0.38) | TSHRMMP12PRSS1CTSGCTRB1 | |
| SCHEMBL5855412 | 0.78 | TDP1 (0.39) | TSHRMMP12PRSS1CTSGCTRB1 | |
| SCHEMBL5855399 | 0.78 | TDP1 (0.39) | TSHRMMP12PRSS1CTSGCTRB1 | |
| SCHEMBL17460916 | 0.77 | PRSS1 (0.36) | MMP12PRSS1SMN1; SMN2CTSGCTRB1 | |
| SCHEMBL6139453 | 0.77 | PRSS1 (0.36) | MMP12PRSS1SMN1; SMN2CTSGCTRB1 | |
| SCHEMBL16503510 | 0.77 | TSHR (0.44) | TSHRKMT2AMEN1HTTHPGD | |
| SCHEMBL16503522 | 0.77 | TSHR (0.44) | TSHRKMT2AMEN1HTTHPGD | |
| SCHEMBL14016225 | 0.77 | TSHR (0.54) | TSHRMMP12PRSS1F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079869-B2 | Chiral disulfonimides | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2015-07-14 | — | — | US | disclosed |
| US-20110313150-A1 | CHIRAL DISULFONIMIDES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110313150-A1 | CHIRAL DISULFONIMIDES | STS, SUDS3, SF1 | TSHR 4279/4885MMP12 4442/4885PRSS1 1540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.