SCHEMBL16503907

SCHEMBL16503907

Cc1cc(OC2CCN(C(=O)OC(C)C)CC2)ncn1

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.58
CYP2C9 P11712 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL288373 0.88 GPR119 (0.58) GPR119CYP2C9
SCHEMBL15114919 0.83 NAMPT (0.45) GPR119
SCHEMBL2524108 0.83 GPR119 (0.57) GPR119
SCHEMBL13107758 0.81 GPR119 (0.74) GPR119CYP2C9
SCHEMBL4263519 0.80 GPR119 (0.75) GPR119CYP2C9
SCHEMBL386785 0.80 GPR119 (0.80) GPR119CYP2C9
SCHEMBL390248 0.79 GPR119 (0.64) GPR119CYP2C9
SCHEMBL390523 0.79 GPR119 (0.64) GPR119CYP2C9
SCHEMBL390044 0.79 GPR119 (0.63) GPR119CYP2C9
SCHEMBL389562 0.79 GPR119 (0.71) GPR119CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2399914-A1 FUSED HETEROCYCLIC RING COMPOUND Takeda Pharmaceutical Company Limited (JP) 2011-12-28 EP disclosed