Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 7/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 5/20 | 0.34 |
| ▸ | ACE | P12821 | 3/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mertiatide SCHEMBL136462 | 0.95 | ALDH1A1 (0.41) | ALDH1A1MAPTTDP1LMNAPTGS2 | |
| SCHEMBL1493216 | 0.95 | ALDH1A1 (0.41) | ALDH1A1MAPTTDP1LMNAPTGS2 | |
| SCHEMBL14417106 | 0.95 | ALDH1A1 (0.41) | ALDH1A1MAPTTDP1LMNAPTGS2 | |
| Mertiatide SCHEMBL23522195 | 0.93 | ALDH1A1 (0.40) | ALDH1A1MAPTTDP1LMNAPTGS2 | |
| SCHEMBL2796838 | 0.93 | ALDH1A1 (0.40) | ALDH1A1MAPTTDP1LMNAPTGS2 | |
| SCHEMBL75812 | 0.91 | — | — | |
| SCHEMBL12762758 | 0.84 | ALDH1A1 (0.34) | ALDH1A1MAPTTDP1LMNAPTGS2 | |
| Glycine SCHEMBL4653213 | 0.82 | GLRA1 (0.46) | ALDH1A1MAPTTDP1LMNAPTGS2 | |
| Glycine SCHEMBL4264488 | 0.82 | GLRA1 (0.46) | ALDH1A1MAPTTDP1LMNAPTGS2 | |
| SCHEMBL610938 | 0.80 | ALDH1A1 (0.38) | ALDH1A1MAPTTDP1LMNAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |