⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1373372 | 0.98 | HSD17B10 (0.42) | — | |
| SCHEMBL4768884 | 0.86 | HSD17B10 (0.52) | — | |
| Hydrochloric Acid SCHEMBL1371867 | 0.84 | HSD17B10 (0.50) | — | |
| SCHEMBL1007971 | 0.80 | — | — | |
| SCHEMBL5322238 | 0.80 | — | — | |
| SCHEMBL7428460 | 0.75 | CYP1A2 (0.55) | — | |
| SCHEMBL27554373 | 0.74 | — | — | |
| SCHEMBL9036691 | 0.74 | ALDH1A1 (0.55) | — | |
| Tetraxetan SCHEMBL18018 | 0.72 | HSD17B10 (0.64) | — | |
| SCHEMBL173508 | 0.72 | HSD17B10 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705052-B2 | Sulfonamide derivatives for the treatment of diabetes | MERCK SERONO SA (CH) | 2010-04-27 | — | — | US | claimed |
| CN-119737179-A | Magnetically-expanded self-fastening anchor rod material and preparation method thereof | 中煤科工开采研究院有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-117624074-A | Preparation method of high-purity epalrestat A crystal form | 哈药集团技术中心 | 2024-03-01 | — | — | CN | disclosed |
| CN-116003604-A | Epithelial cadherin-specific antibodies | 科凌生物医疗有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-115066439-A | Epithelial cadherin-specific antibodies | 科凌生物医疗有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-114907286-A | Preparation method of high-purity epalrestat crystal | 山东达因海洋生物制药股份有限公司 | 2022-08-16 | — | — | CN | disclosed |
| US-20140107116-A1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | MERCK SERONO SA (CH) | 2014-04-17 | — | — | US | disclosed |
| WO-2011149841-A1 | SUBSTITUTED THIAZOLIDINEDIONE INDAZOLES, INDOLES AND BENZOTRIAZOLES AS ESTROGEN-RELATED RECEPTOR-α MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-12-01 | — | — | WO | disclosed |
| EP-1656139-B1 | ARYL DICARBOXAMIDES | MERCK SERONO SA (CH) | 2011-10-05 | — | — | EP | disclosed |
| EP-1470102-B1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | MERCK SERONO SA (CH) | 2011-05-25 | — | — | EP | disclosed |
| WO-2005025567-A1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-03-24 | — | — | WO | disclosed |
| WO-2005025558-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DIABETES | APPLIED RESERACH SYSTEMS ARS HOLDING N.V. (AN) | 2005-03-24 | — | — | WO | disclosed |
| WO-2005012280-A1 | ALKYNYL ARYL CARBOXAMIDES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-02-10 | — | — | WO | disclosed |
| WO-2005011685-A1 | ARYL DICARBOXAMIDES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | disclosed |
| EP-1313471-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | Oxford GlycoSciences (UK) Limited (GB) | 2003-05-28 | — | — | EP | disclosed |
| US-20020198201-A1 | Combination of a PTPase inhibitor and an aldose reductase inhibitor | WYETH | 2002-12-26 | — | — | US | disclosed |
| WO-2002098510-A1 | COMBINATION OF A PTPASE INHIBITOR AND AN ALDOSE REDUCTASE INHIBITOR | WYETH (US) | 2002-12-12 | — | — | WO | disclosed |
| WO-2002017915-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | OXFORD GLYCOSCIENCES (UK) LIMITED (GB) | 2002-03-07 | — | — | WO | disclosed |