Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 1.00 |
| ▸ | THRB | P10828 | 9/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 9/20 | 1.00 |
| ▸ | BLM | P54132 | 8/20 | 1.00 |
| ▸ | RECQL | P46063 | 7/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | HTT | P42858 | 5/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 1.00 |
| ▸ | APEX1 | P27695 | 3/20 | 1.00 |
| ▸ | BRCA1 | P38398 | 6/20 | 0.87 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.87 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.87 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.87 |
| ▸ | S100A4 | P26447 | 5/20 | 0.87 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.87 |
| ▸ | USP2 | O75604 | 4/20 | 0.87 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.87 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.87 |
| ▸ | TOP2A | P11388 | 4/20 | 0.87 |
| ▸ | STAT6 | P42226 | 4/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carubicin SCHEMBL9552 | 1.00 | MEN1 (1.00) | MEN1THRBKMT2ABLMRECQL | |
| Carubicin SCHEMBL6343014 | 1.00 | MEN1 (1.00) | MEN1THRBKMT2ABLMRECQL | |
| Carubicin SCHEMBL29362266 | 1.00 | MEN1 (1.00) | MEN1THRBKMT2ABLMRECQL | |
| Carubicin SCHEMBL12202628 | 1.00 | MEN1 (1.00) | MEN1THRBKMT2ABLMRECQL | |
| Carubicin SCHEMBL6343007 | 1.00 | MEN1 (1.00) | MEN1THRBKMT2ABLMRECQL | |
| Carubicin SCHEMBL23300868 | 1.00 | MEN1 (1.00) | MEN1THRBKMT2ABLMRECQL | |
| Carubicin SCHEMBL18389599 | 1.00 | MEN1 (1.00) | MEN1THRBKMT2ABLMRECQL | |
| Carubicin SCHEMBL29357994 | 0.99 | MEN1 (0.98) | MEN1THRBKMT2ABLMRECQL | |
| Carubicin SCHEMBL29355094 | 0.99 | MEN1 (0.98) | MEN1THRBKMT2ABLMRECQL | |
| Carubicin SCHEMBL4201 | 0.99 | MEN1 (0.98) | MEN1THRBKMT2ABLMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9035032-B2 | Method for preparing 4-demethyldaunorubicin | SOLUX CORPORATION (US) | 2015-05-19 | — | — | US | disclosed |
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |
| US-7553816-B2 | p-amidobenzylethers in drug delivery agents | SEATTLE GENETICS, INC. (US) | 2009-06-30 | — | — | US | disclosed |