Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16506093 | 0.92 | MAP3K14 (0.56) | MAP3K14PKD1 | |
| SCHEMBL16505956 | 0.88 | MAP3K14 (0.60) | MAP3K14PKD1 | |
| SCHEMBL16505404 | 0.79 | MAP3K14 (0.68) | MAP3K14PKD1 | |
| SCHEMBL16505523 | 0.79 | MAP3K14 (0.68) | MAP3K14PKD1 | |
| SCHEMBL16505739 | 0.77 | MAP3K14 (0.61) | MAP3K14PKD1 | |
| SCHEMBL16522805 | 0.76 | MAP3K14 (0.60) | MAP3K14PKD1 | |
| SCHEMBL16505563 | 0.76 | MAP3K14 (0.60) | MAP3K14PKD1 | |
| SCHEMBL16522817 | 0.76 | MAP3K14 (0.67) | MAP3K14PKD1 | |
| SCHEMBL16505271 | 0.76 | MAP3K14 (0.58) | MAP3K14PKD1 | |
| SCHEMBL16505660 | 0.75 | MAP3K14 (0.64) | MAP3K14PKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150057260-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | GENENTECH, INC. (US) | 2015-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150057260-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | NFKB2, NFKB1, NFKBIA | MAP3K14 553/4885PKD1 2437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.