SCHEMBL16506352

SCHEMBL16506352

CC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)O.O=C(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.65
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4395001 0.94 THRB (0.54) THRB
SCHEMBL14879618 0.94 THRB (0.54) THRB
SCHEMBL1491941 0.94 THRB (0.54) THRB
Ammonia Solution, Strong SCHEMBL28635848 0.92 THRB (0.52) THRB
SCHEMBL6514807 0.86 THRB (0.46) THRB
SCHEMBL11618473 0.84 THRB (0.71) THRBCA1CA2
Isopropyl Alcohol SCHEMBL28348132 0.84 THRB (0.77) THRBCA1CA2MMP1MMP2
Fluoromethane SCHEMBL27867584 0.81 THRB (0.90) THRBCA1CA2MMP1MMP2
Ethane SCHEMBL28102526 0.81 THRB (0.90) THRBCA1CA2MMP1MMP2
Fluoromethane SCHEMBL21437550 0.81 THRB (0.90) THRBCA1CA2MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150053620-A1 WATER TREATMENT TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2015-02-26 US claimed
EP-3036198-A1 WATER TREATMENT FOR REMOVAL OF ENDOCRINE DISRUPTING CHEMICALS Temple University Of The Commonwealth System Of Higher Education (US) 2016-06-29 EP disclosed
US-20150053620-A1 WATER TREATMENT TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2015-02-26 US disclosed