Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.44 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 4/20 | 0.42 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.42 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.42 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.42 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.42 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12293625 | 0.97 | NNMT (0.48) | NNMTPLAUKDM4ACACNA1BKLKB1 | |
| SCHEMBL13724136 | 0.97 | NNMT (0.48) | NNMTPLAUKDM4ACACNA1BKLKB1 | |
| SCHEMBL13724891 | 0.96 | NNMT (0.47) | NNMTPLAUKDM4ACACNA1BKLKB1 | |
| SCHEMBL12293481 | 0.96 | NNMT (0.47) | NNMTPLAUKDM4ACACNA1BKLKB1 | |
| SCHEMBL13723864 | 0.96 | NNMT (0.46) | NNMTPLAUKDM4ACACNA1BKLKB1 | |
| SCHEMBL13724286 | 0.96 | NNMT (0.46) | NNMTPLAUKDM4ACACNA1BKLKB1 | |
| SCHEMBL13724709 | 0.95 | PLAU (0.48) | NNMTPLAUKDM4ACACNA1BKLKB1 | |
| SCHEMBL13722938 | 0.94 | PLAU (0.50) | NNMTPLAUKDM4ACACNA1BKLKB1 | |
| SCHEMBL13725054 | 0.94 | NNMT (0.50) | NNMTPLAUKDM4ACACNA1BKLKB1 | |
| SCHEMBL13724150 | 0.94 | NNMT (0.50) | NNMTPLAUKDM4ACACNA1BKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076285-B2 | Lysobactin amides | AICURIS GMBH & CO. KG (DE) | 2011-12-13 | — | — | US | disclosed |
| US-8076285-B2 | Lysobactin amides | AICURIS GMBH & CO. KG (DE) | 2011-12-13 | — | — | US | disclosed |