Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI | P10646 | 1/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.47 |
| ▸ | IL23R | Q5VWK5 | 4/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.43 |
| ▸ | VIPR1 | P32241 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16508127 | 0.91 | TFPI (0.51) | TFPIOPRL1IL23RKEAP1VIPR1 | |
| SCHEMBL16507872 | 0.86 | IL23R (0.45) | TFPIOPRL1IL23R | |
| SCHEMBL30432032 | 0.86 | OPRL1 (0.48) | TFPIOPRL1VIPR1 | |
| SCHEMBL16508548 | 0.85 | SIRT5 (0.44) | TFPIOPRL1IL23R | |
| SCHEMBL16508436 | 0.85 | SIRT5 (0.44) | TFPIIL23R | |
| SCHEMBL16507939 | 0.84 | GLP1R (0.46) | TFPIOPRL1 | |
| SCHEMBL16507960 | 0.84 | GLP1R (0.46) | TFPIOPRL1 | |
| SCHEMBL16507786 | 0.84 | GLP1R (0.46) | TFPIOPRL1 | |
| SCHEMBL16507873 | 0.84 | GLP1R (0.45) | TFPIOPRL1 | |
| SCHEMBL16507777 | 0.83 | OPRL1 (0.46) | TFPIOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110294738-A1 | PTHR1 RECEPTOR COMPOUNDS | ANTHOR THERAPEUTICS, INC. | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294738-A1 | PTHR1 RECEPTOR COMPOUNDS | PTH1R, MC1R, CASR | TFPI 2646/4885OPRL1 335/4885IL23R 1779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.