SCHEMBL16508061

SCHEMBL16508061

CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C)CC(C)C)[C@@H](C)O)C(C)C

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ RXFP1 Q9HBX9 6/20 0.54
▸ TFPI P10646 1/20 0.50
▸ PRSS1 P07477 1/20 0.50
▸ FURIN P09958 1/20 0.50
▸ GLP1R P43220 2/20 0.49
▸ GCGR P47871 1/20 0.49
▸ GIPR P48546 1/20 0.49
▸ TLR2 O60603 1/20 0.48
▸ NPY5R Q15761 3/20 0.48
▸ NPY1R P25929 2/20 0.48
▸ NPY4R P50391 2/20 0.48
▸ NMT2 O60551 1/20 0.47
▸ NMT1 P30419 1/20 0.47
▸ ECE1 P42892 1/20 0.47
▸ MUS81 Q96NY9 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13363672 0.95 RXFP1 (0.54) RXFP1TFPIPRSS1FURINGLP1R
SCHEMBL16507926 0.94 NPY4R (0.53) RXFP1PRSS1FURINGLP1RGCGR
SCHEMBL16507959 0.92 RXFP1 (0.59) RXFP1TFPIGLP1RGCGRGIPR
SCHEMBL16508129 0.88 NPY4R (0.52) RXFP1PRSS1FURINGLP1RGCGR
SCHEMBL16508088 0.85 NPY4R (0.51) RXFP1TFPIPRSS1FURINGLP1R
SCHEMBL16507762 0.85 TFPI (0.56) RXFP1TFPIGLP1RGCGRGIPR
SCHEMBL16507937 0.84 RXFP1 (0.55) RXFP1TFPIGLP1RGCGRGIPR
SCHEMBL16507855 0.84 RXFP1 (0.55) RXFP1TFPIGLP1RGCGRGIPR
SCHEMBL16976058 0.84 NPY4R (0.60) RXFP1TLR2NPY5RNPY1RNPY4R
SCHEMBL15186049 0.84 ECE1 (0.60) GLP1RECE1MUS81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS ANTHOR THERAPEUTICS, INC. 2011-12-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS PTH1R, MC1R, CASR RXFP1 568/4885TFPI 2646/4885PRSS1 3044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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