SCHEMBL16507937

SCHEMBL16507937

CCCCCCCCCCCCCCCC(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)NC)[C@@H](C)O)[C@H](C)O)C(C)C

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ RXFP1 Q9HBX9 6/20 0.55
▸ GLP1R P43220 1/20 0.50
▸ GCGR P47871 1/20 0.50
▸ GIPR P48546 1/20 0.50
▸ NPY5R Q15761 5/20 0.49
▸ NPY1R P25929 4/20 0.49
▸ NPY4R P50391 4/20 0.49
▸ TFPI P10646 1/20 0.46
▸ NPY2R P49146 2/20 0.44
▸ VIPR2 P41587 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16507855 0.99 RXFP1 (0.55) RXFP1GLP1RGCGRGIPRNPY5R
SCHEMBL16508129 0.95 NPY4R (0.52) RXFP1GLP1RGCGRGIPRNPY5R
SCHEMBL16507926 0.90 NPY4R (0.53) RXFP1GLP1RGCGRGIPRNPY5R
SCHEMBL16508517 0.90 NPY4R (0.59) RXFP1GLP1RGCGRGIPRNPY5R
SCHEMBL16507959 0.89 RXFP1 (0.59) RXFP1GLP1RGCGRGIPRTFPI
SCHEMBL16509117 0.89 NPY4R (0.57) RXFP1GLP1RGCGRGIPRNPY5R
SCHEMBL16509029 0.86 NPY4R (0.51) RXFP1GLP1RGCGRGIPRNPY5R
SCHEMBL31130725 0.86 NPY4R (0.53) RXFP1GLP1RGCGRGIPRNPY5R
SCHEMBL16509119 0.86 NPY4R (0.51) RXFP1GLP1RGCGRGIPRNPY5R
SCHEMBL16508131 0.85 RXFP1 (0.57) RXFP1GLP1RGCGRGIPRNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS ANTHOR THERAPEUTICS, INC. 2011-12-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS PTH1R, MC1R, CASR RXFP1 568/4885GLP1R 120/4885GCGR 171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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