SCHEMBL16508108

SCHEMBL16508108

C[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)[C@@H](C)O

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 12/20 0.57
▸ NPY5R Q15761 8/20 0.57
▸ NPY1R P25929 8/20 0.57
▸ NPY2R P49146 5/20 0.57
▸ IL23R Q5VWK5 3/20 0.54
▸ KISS1R Q969F8 4/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16508074 0.94 IL23R (0.55) NPY4RNPY5RNPY1RNPY2RIL23R
SCHEMBL16508142 0.93 KISS1R (0.58) NPY4RNPY5RNPY1RNPY2RIL23R
SCHEMBL16508093 0.91 TFPI (0.63) NPY4RNPY5RNPY1RNPY2RIL23R
SCHEMBL16507968 0.90 NPY4R (0.60) NPY4RNPY5RNPY1RNPY2RIL23R
SCHEMBL16507918 0.90 NPY4R (0.61) NPY4RNPY5RNPY1RNPY2RIL23R
SCHEMBL16507868 0.89 NPY4R (0.58) NPY4RNPY5RNPY1RNPY2RIL23R
SCHEMBL16508147 0.88 TFPI (0.61) NPY4RNPY5RNPY1RNPY2RKISS1R
SCHEMBL16507955 0.88 NPY4R (0.66) NPY4RNPY5RNPY1RNPY2R
SCHEMBL16507943 0.88 TFPI (0.57) NPY4RNPY5RNPY1RNPY2RIL23R
SCHEMBL16507944 0.87 NPY5R (0.62) NPY4RNPY5RNPY1RNPY2RIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS ANTHOR THERAPEUTICS, INC. 2011-12-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS PTH1R, MC1R, CASR NPY4R 1387/4885NPY5R 1478/4885NPY1R 800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback