SCHEMBL16508131

SCHEMBL16508131

CCCCCCCCCCCCCCCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(C)=O)[C@@H](C)O)C(C)C)C(C)C)[C@@H](C)CC

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ RXFP1 Q9HBX9 4/20 0.57
▸ VIPR2 P41587 2/20 0.50
▸ NPY5R Q15761 3/20 0.49
▸ NPY1R P25929 2/20 0.49
▸ NPY4R P50391 2/20 0.49
▸ GLP1R P43220 1/20 0.49
▸ GCGR P47871 1/20 0.49
▸ GIPR P48546 1/20 0.49
▸ VIPR1 P32241 2/20 0.48
▸ MAPK8 P45983 1/20 0.48
▸ MAPK9 P45984 1/20 0.48
▸ MAPK10 P53779 1/20 0.48
▸ TFPI P10646 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16507926 0.88 NPY4R (0.53) RXFP1NPY5RNPY1RNPY4RGLP1R
SCHEMBL16508129 0.87 NPY4R (0.52) RXFP1NPY5RNPY1RNPY4RGLP1R
SCHEMBL16507762 0.85 TFPI (0.56) RXFP1GLP1RGCGRGIPRTFPI
SCHEMBL16507937 0.85 RXFP1 (0.55) RXFP1VIPR2NPY5RNPY1RNPY4R
SCHEMBL16507855 0.85 RXFP1 (0.55) RXFP1VIPR2NPY5RNPY1RNPY4R
SCHEMBL13363672 0.84 RXFP1 (0.54) RXFP1NPY5RNPY1RNPY4RGLP1R
SCHEMBL16507959 0.83 RXFP1 (0.59) RXFP1GLP1RGCGRGIPRTFPI
SCHEMBL10168810 0.82 NPY5R (0.50) RXFP1NPY5RNPY1RNPY4RGLP1R
SCHEMBL16508090 0.82 NPY4R (0.58) RXFP1NPY5RNPY1RNPY4RGLP1R
SCHEMBL31130725 0.82 NPY4R (0.53) RXFP1NPY5RNPY1RNPY4RGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS ANTHOR THERAPEUTICS, INC. 2011-12-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS PTH1R, MC1R, CASR RXFP1 568/4885VIPR2 843/4885NPY5R 1478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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