Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 4/20 | 0.39 |
| ▸ | BPTF | Q12830 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15580048 | 0.89 | MAPK1 (0.36) | MAPK1IKBKBBPTFL3MBTL1APAF1 | |
| SCHEMBL16508157 | 0.86 | IKBKB (0.42) | MAPK1IKBKBL3MBTL1APAF1NSD2 | |
| SCHEMBL21992059 | 0.86 | PDE4A (0.35) | MAPK1IKBKBBPTFL3MBTL1TSHR | |
| SCHEMBL16573178 | 0.85 | IKBKB (0.37) | MAPK1IKBKBL3MBTL1APAF1NSD2 | |
| SCHEMBL21992070 | 0.85 | IKBKB (0.37) | MAPK1IKBKBPARP10IRAK4TSHR | |
| SCHEMBL16508203 | 0.85 | IKBKB (0.39) | MAPK1IKBKBBPTFL3MBTL1APAF1 | |
| SCHEMBL16573139 | 0.84 | IKBKB (0.36) | MAPK1IKBKBL3MBTL1APAF1NSD2 | |
| SCHEMBL16508183 | 0.83 | IKBKB (0.39) | MAPK1IKBKBL3MBTL1APAF1NSD2 | |
| SCHEMBL16258541 | 0.83 | IKBKB (0.36) | MAPK1IKBKBL3MBTL1APAF1NSD2 | |
| SCHEMBL16573179 | 0.83 | IKBKB (0.37) | MAPK1IKBKBBPTFL3MBTL1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3106461-B1 | DERIVATIVES OF UK-2A | DOW AGROSCIENCES LLC (US) | 2020-05-06 | — | — | EP | disclosed |
| EP-3106461-A1 | DERIVATIVES OF UK-2A | Dow AgroSciences LLC (US) | 2016-12-21 | — | — | EP | disclosed |
| EP-2848616-A1 | Derivatives of UK-2A | Dow AgroSciences LLC (US) | 2015-03-18 | — | — | EP | disclosed |
| EP-2527342-A2 | Derivatives of UK-2A | Dow AgroSciences LLC (US) | 2012-11-28 | — | — | EP | disclosed |