Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16508234 | 0.89 | SMN1; SMN2 (0.37) | IKBKBSMN1; SMN2KDM4ELMNACYP1A2 | |
| SCHEMBL16508155 | 0.85 | MAPK1 (0.40) | IKBKBSMN1; SMN2APAF1NSD2CASP3 | |
| SCHEMBL19604244 | 0.83 | IKBKB (0.38) | IKBKBSMN1; SMN2KDM4ELMNACYP1A2 | |
| SCHEMBL16508157 | 0.83 | IKBKB (0.42) | IKBKBAPAF1NSD2CASP3SENP8 | |
| SCHEMBL16573137 | 0.82 | IKBKB (0.36) | IKBKBSMN1; SMN2KDM4ELMNACYP1A2 | |
| SCHEMBL16573133 | 0.82 | IKBKB (0.39) | IKBKBSMN1; SMN2KDM4ELMNACYP1A2 | |
| SCHEMBL16573139 | 0.81 | IKBKB (0.36) | IKBKBSMN1; SMN2APAF1NSD2CASP3 | |
| SCHEMBL16258571 | 0.81 | IKBKB (0.36) | IKBKBSMN1; SMN2KDM4ELMNACYP1A2 | |
| SCHEMBL16508183 | 0.80 | IKBKB (0.39) | IKBKBSMN1; SMN2KDM4ELMNACYP1A2 | |
| SCHEMBL16573177 | 0.80 | IKBKB (0.36) | IKBKBSMN1; SMN2KDM4ELMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3106461-B1 | DERIVATIVES OF UK-2A | DOW AGROSCIENCES LLC (US) | 2020-05-06 | — | — | EP | disclosed |
| EP-2848616-B1 | Derivatives of UK-2A | DOW AGROSCIENCES LLC (US) | 2016-11-23 | — | — | EP | disclosed |
| EP-2848616-A1 | Derivatives of UK-2A | Dow AgroSciences LLC (US) | 2015-03-18 | — | — | EP | disclosed |