Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | NNMT | P40261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5008136 | 0.85 | IKBKB (0.46) | IKBKBL3MBTL1APAF1NSD2CASP3 | |
| SCHEMBL21992262 | 0.84 | IKBKB (0.40) | IKBKBL3MBTL1APAF1NSD2CASP3 | |
| SCHEMBL16508183 | 0.82 | IKBKB (0.39) | IKBKBL3MBTL1APAF1NSD2CASP3 | |
| SCHEMBL16508155 | 0.82 | MAPK1 (0.40) | IKBKBL3MBTL1APAF1NSD2CASP3 | |
| SCHEMBL16573170 | 0.82 | IKBKB (0.37) | IKBKBL3MBTL1APAF1NSD2CASP3 | |
| SCHEMBL16573133 | 0.81 | IKBKB (0.39) | IKBKBL3MBTL1APAF1NSD2CASP3 | |
| SCHEMBL21992245 | 0.81 | IKBKB (0.39) | IKBKBL3MBTL1APAF1NSD2CASP3 | |
| SCHEMBL16508203 | 0.81 | IKBKB (0.39) | IKBKBL3MBTL1APAF1NSD2CASP3 | |
| SCHEMBL21976891 | 0.81 | IKBKB (0.43) | IKBKBL3MBTL1APAF1NSD2CASP3 | |
| SCHEMBL16573130 | 0.81 | IKBKB (0.38) | IKBKBL3MBTL1APAF1NSD2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2527342-A2 | Derivatives of UK-2A | Dow AgroSciences LLC (US) | 2012-11-28 | — | — | EP | disclosed |