⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL763790 | 0.81 | KIF11 (0.37) | — | |
| Ammonia Solution, Strong SCHEMBL735815 | 0.78 | KIF11 (0.36) | — | |
| Hydrochloric Acid SCHEMBL20637046 | 0.78 | KIF11 (0.36) | — | |
| SCHEMBL15256844 | 0.72 | KIF11 (0.37) | — | |
| SCHEMBL19226326 | 0.70 | — | — | |
| SCHEMBL18814890 | 0.70 | — | — | |
| SCHEMBL20644946 | 0.68 | KIF11 (0.30) | — | |
| SCHEMBL18217824 | 0.68 | CA12 (0.35) | — | |
| SCHEMBL15782757 | 0.67 | — | — | |
| SCHEMBL9886710 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110305770-A1 | RELEASABLE POLYMERIC LIPIDS FOR NUCLEIC ACIDS DELIVERY SYSTEM | ENZON PHARMACEUTICALS, INC. (US) | 2011-12-15 | — | — | US | disclosed |