Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | FURIN | P09958 | 1/20 | 0.37 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | NPY4R | P50391 | 4/20 | 0.35 |
| ▸ | NPY1R | P25929 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193414 | 0.91 | OPRK1 (0.42) | NMT2NMT1ERAP2ERAP1LNPEP | |
| SCHEMBL2182039 | 0.91 | OPRK1 (0.42) | NMT2NMT1ERAP2ERAP1LNPEP | |
| SCHEMBL2195069 | 0.91 | OPRK1 (0.42) | NMT2NMT1ERAP2ERAP1LNPEP | |
| SCHEMBL2182536 | 0.91 | OPRK1 (0.42) | NMT2NMT1ERAP2ERAP1LNPEP | |
| SCHEMBL2182926 | 0.91 | OPRK1 (0.42) | NMT2NMT1ERAP2ERAP1LNPEP | |
| SCHEMBL2196205 | 0.86 | NMT1 (0.43) | NMT2NMT1ERAP2ERAP1LNPEP | |
| SCHEMBL2190396 | 0.86 | NPY4R (0.43) | NMT2NMT1ERAP2ERAP1LNPEP | |
| SCHEMBL31211799 | 0.86 | ERAP2 (0.51) | NMT2NMT1ERAP2ERAP1LNPEP | |
| SCHEMBL16468902 | 0.85 | NPY4R (0.51) | NMT2NMT1NPY4RNPY1RNPY2R | |
| SCHEMBL2196613 | 0.85 | DPP4 (0.41) | DPP8DPP9DPP4BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |