Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAC1 | P63000 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12072037 | 0.94 | SMN1; SMN2 (0.45) | KDM4EMAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL12070673 | 0.91 | RAC1 (0.49) | KDM4EMAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL14927009 | 0.87 | MEN1 (0.42) | KDM4EMAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL12072698 | 0.85 | SMN1; SMN2 (0.48) | KDM4EMAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL16510759 | 0.81 | KDM4E (0.45) | KDM4EMAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL14927007 | 0.80 | MEN1 (0.43) | KDM4EMAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL16510485 | 0.80 | KDM4E (0.63) | KDM4EMAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL12070517 | 0.77 | USP2 (0.44) | KDM4EMAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL147920 | 0.77 | RAC1 (0.71) | KDM4EMAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL215619 | 0.76 | RAC1 (0.73) | KDM4EMAPTSMN1; SMN2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011156626-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-12-15 | — | — | WO | disclosed |