Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.43 |
| ▸ | RAC1 | P63000 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12070673 | 0.83 | RAC1 (0.49) | USP2CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL12072698 | 0.81 | SMN1; SMN2 (0.48) | USP2CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL14926984 | 0.81 | PDCD1 (0.47) | USP2CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL12072675 | 0.78 | PDE10A (0.43) | USP2CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL16510758 | 0.77 | KDM4E (0.45) | USP2CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL12074884 | 0.77 | PDGFRB (0.45) | USP2CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL12072037 | 0.76 | SMN1; SMN2 (0.45) | USP2CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL16383319 | 0.75 | ACACA (0.38) | HSD17B10ALDH1A1LMNAACACAPDCD1 | |
| SCHEMBL14926987 | 0.72 | USP2 (0.40) | USP2CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL12074044 | 0.71 | PDGFRB (0.72) | ALDH1A1GAASMN1; SMN2MAPTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933096-B2 | Antimicrobial agents | Rugers, The State University of New Jersey (US) | 2015-01-13 | — | — | US | disclosed |
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2013-05-09 | — | — | US | disclosed |
| WO-2011159926-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-12-22 | — | — | WO | disclosed |
| WO-2011156626-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | MRPL21, ARG1, RPP30 | USP2 4630/4885CYP1A2 2201/4885CYP3A4 2285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.