Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16511967 | 0.99 | MAPT (0.35) | MAPTTP53POLBTHRBLMNA | |
| SCHEMBL16511711 | 0.89 | POLB (0.39) | MAPTTP53POLBTHRBLMNA | |
| SCHEMBL16511693 | 0.88 | MAPT (0.37) | MAPTTP53POLBTHRBLMNA | |
| SCHEMBL16511897 | 0.87 | POLB (0.38) | MAPTTP53POLBTHRBLMNA | |
| SCHEMBL16511689 | 0.86 | MAPT (0.36) | MAPTTP53POLBTHRBLMNA | |
| SCHEMBL16511709 | 0.86 | MAPT (0.36) | MAPTTP53POLBTHRBLMNA | |
| SCHEMBL16511713 | 0.86 | MAPT (0.36) | MAPTTP53POLBTHRBLMNA | |
| SCHEMBL16511893 | 0.84 | MAPT (0.34) | MAPTTP53POLBTHRBLMNA | |
| SCHEMBL16511894 | 0.84 | MAPT (0.34) | MAPTTP53POLBTHRBLMNA | |
| SCHEMBL16511965 | 0.84 | MAPT (0.34) | MAPTTP53POLBTHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011153866-A1 | 3-(0-METHYLPHENYL)-2-OXO-L-OXASPIRO[4,5]-DEC-3-EN-4-OL DERIVATIVES WITH INSECTICIDAL, ACARICIDAL AND FUNGICIDAL ACTIVITIES AND THEIR PREPARATION METHODS | 湖南化工研究院 (CN) | 2011-12-15 | — | — | WO | disclosed |