SCHEMBL165172

SCHEMBL165172

Nc1ncc(Br)nc1N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29912802 1.00
SCHEMBL41047 0.80
SCHEMBL274632 0.80
SCHEMBL29457483 0.80
SCHEMBL5560606 0.78
SCHEMBL1255045 0.76
SCHEMBL2628998 0.76
SCHEMBL16268615 0.76
SCHEMBL21497161 0.76
SCHEMBL12847283 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117946366-A Preparation method of biomass-based waterborne polyurethane, textile and leather 浙江梅盛新材料有限公司 2024-04-30 CN claimed
CN-116283984-A Organic thermal delay fluorescent material based on di-tert-butylaniline donor and preparation method thereof 电子科技大学 2023-06-23 CN claimed
CN-102225918-A 1,2,3-thiadiazole formyl urea compounds as well as preparation method and application thereof LIER CHEMICAL CO LTD 2011-10-26 CN claimed
CN-102174029-A Di(5-methyl-1,2,3-thiadiazole-4-formoxyl urea) compounds, and preparation method and application thereof UNIV NANKAI 2011-09-07 CN claimed
US-20110098310-A1 NOVEL COMPOUNDS, USE AND PREPARATION THEREOF BIOVITRUM AB (SE) 2011-04-28 US claimed
JP-2011510948-A 2011-04-07 JP claimed
CN-101970418-A Novel compounds, use and preparation thereof AKINION PHARMACEUTICALS AB 2011-02-09 CN claimed
EP-2252597-A2 NOVEL COMPOUNDS, USE AND PREPARATION THEREOF Akinion Pharmaceuticals AB (SE) 2010-11-24 EP claimed
WO-2009095399-A2 PYRAZINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHBITORS AKINION PHARMACEUTICALS AB (SE) 2009-08-06 WO claimed
EP-4727652-A1 (HETERO)ARYL-SULFONAMIDE COMPOUNDS AS MODULATORS OF GPR35 ThirtyFiveBio Limited (GB) 2026-04-22 EP disclosed
EP-4676926-A1 BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS ThirtyFiveBio Limited (GB) 2026-01-14 EP disclosed
US-20250213571-A1 TYK2 INHIBITORS AND USES THEREOF ALUMIS INC. 2025-07-03 US disclosed
US-20250034170-A1 SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF VANQUA BIO, INC. (US) 2025-01-30 US disclosed
EP-4493562-A1 TYK2 INHIBITORS AND USES THEREOF Alumis Inc. (US) 2025-01-22 EP disclosed
WO-2006125958-A1 2-PHENYL SUBSTITUTED IMIDAZOL [4 , 5B] PYRIDINE/ PYRAZINE AND PURINE DERIVATIVES AS GLUCOKINASE MODULATORS ASTRAZENECA AB (SE) 2006-11-30 WO disclosed
WO-2006114272-A1 FURAN COMPOUNDS USEFUL AS EPl RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2006-11-02 WO disclosed
US-20060142307-A1 Aminopyrazine analogs for treating glaucoma and other rho kinase-mediated diseases and conditions ALCON, INC. 2006-06-29 US disclosed
WO-2006039325-A2 AMINOPIPERIDINES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES MERCK & CO., INC. (US) 2006-04-13 WO disclosed
WO-2004112714-A2 CHEMICAL COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2004-12-29 WO disclosed
WO-2004085409-A2 COMPOUNDS AND LIBRARIES OF PYRIDINES, PYRAZINES, IMIDAZO[1,2-A]PYRAZINES AND 1H-IMIDAZO[4,5-B]PYRAZIN-2-ONES AND FIRST AND SECOND MEDICAL USES THEREOF BIOFOCUS DISCOVERY LTD (GB) 2004-10-07 WO disclosed