Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16187527 | 1.00 | ACACB (0.62) | ACACB | |
| SCHEMBL16187530 | 1.00 | ACACB (0.62) | ACACB | |
| SCHEMBL15048067 | 0.91 | ACACB (0.63) | ACACB | |
| SCHEMBL15048018 | 0.91 | ACACB (0.63) | ACACB | |
| SCHEMBL18176103 | 0.89 | ACACB (0.49) | ACACB | |
| SCHEMBL15634768 | 0.85 | ACACB (0.71) | ACACB | |
| SCHEMBL16214228 | 0.83 | ACACB (0.54) | ACACB | |
| SCHEMBL15247392 | 0.83 | ACACB (0.53) | ACACB | |
| SCHEMBL15048022 | 0.83 | ACACB (0.66) | ACACB | |
| SCHEMBL15901574 | 0.82 | ACACB (0.63) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962641-B2 | Pyrimidine-substituted pyrrolidine derivatives, pharmaceutical compositions and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-24 | — | — | US | disclosed |
| US-8962641-B2 | Pyrimidine-substituted pyrrolidine derivatives, pharmaceutical compositions and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-24 | — | — | US | disclosed |