Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 15/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16187527 | 0.89 | ACACB (0.62) | ACACB | |
| SCHEMBL16187530 | 0.89 | ACACB (0.62) | ACACB | |
| SCHEMBL16518376 | 0.89 | ACACB (0.62) | ACACB | |
| SCHEMBL4315467 | 0.82 | GPR119 (0.57) | GPR119USP30 | |
| SCHEMBL4315470 | 0.82 | GPR119 (0.57) | GPR119USP30 | |
| SCHEMBL20168872 | 0.82 | GPR119 (0.57) | GPR119USP30 | |
| SCHEMBL20179924 | 0.81 | GPR119 (0.58) | GPR119USP30 | |
| SCHEMBL6189661 | 0.81 | GPR119 (0.58) | GPR119USP30 | |
| SCHEMBL15376614 | 0.81 | GPR119 (0.58) | GPR119USP30 | |
| SCHEMBL699609 | 0.81 | GPR119 (0.58) | GPR119USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2948442-B1 | PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2016-10-26 | — | — | EP | disclosed |