Digitoxigenin Gentiobioside

Digitoxigenin Gentiobioside

SCHEMBL1652279

C[C@]12CC[C@@H](O[C@@H]3OC(CO[C@@H]4OC(CO)[C@@H](O)C(O)C4O)[C@@H](O)C(O)C3O)C[C@H]1CCC1C2CC[C@]2(C)[C@@H](C3=CC(=O)OC3)CC[C@]12O

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATP1A1 P05023 12/20 0.92
ATP1B1 P05026 12/20 0.92
ATP1A3 P13637 12/20 0.92
ATP1B2 P14415 12/20 0.92
ATP1A2 P50993 12/20 0.92
ATP1B3 P54709 12/20 0.92
FXYD2 P54710 12/20 0.92
ATP1A4 Q13733 12/20 0.92
PAX8 Q06710 1/20 0.69
TP53 P04637 3/20 0.69
LMNA P02545 2/20 0.69
SMN1; SMN2 Q16637 2/20 0.69
HBB P68871 1/20 0.69
NPC1 O15118 2/20 0.65
RAB9A P51151 2/20 0.65
MAPT P10636 2/20 0.64
USP2 O75604 1/20 0.62
ABCB11 O95342 1/20 0.62
STAT3 P40763 1/20 0.62
SLCO4C1 Q6ZQN7 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Digitoxigenin Gentiobioside SCHEMBL702464 1.00 ATP1A1 (0.92) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
Uzarin SCHEMBL702463 1.00 ATP1A1 (0.92) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
Desglucouzarin SCHEMBL30615298 0.96 ATP1A1 (1.00) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
Thevetin B SCHEMBL869661 0.93 ATP1A1 (0.80) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
Thevetin B SCHEMBL29463277 0.93 ATP1A1 (0.80) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
Thevetin B SCHEMBL29389027 0.93 ATP1A1 (0.80) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
Thevetin B SCHEMBL12556692 0.93 ATP1A1 (0.80) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL29413165 0.93 ATP1A1 (0.79) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL31655532 0.91 ATP1A1 (0.91) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL31135096 0.91 ATP1A1 (0.91) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7927613-B2 Pharmaceutical co-crystal compositions UNIVERSITY OF SOUTH FLORIDA (US) 2011-04-19 US disclosed
US-7790905-B2 Pharmaceutical propylene glycol solvate compositions MCNEIL-PPC, INC. (US) 2010-09-07 US disclosed