SCHEMBL16523116

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17865549	0.91	HRH4 (0.43)	HRH4KMT2AHRH3MEN1NPC1
	SCHEMBL17865567	0.89	HRH4 (0.51)	HRH4KMT2AHRH3MEN1RAB9A
	SCHEMBL22476780	0.86	HRH4 (0.51)	HRH4KMT2AHRH3MEN1NPC1
	SCHEMBL17889903	0.83	HRH4 (0.45)	HRH4KMT2AMEN1RAB9AAKR1C3
	SCHEMBL17865500	0.82	HRH4 (0.51)	HRH4KMT2AHRH3MEN1NPC1
	SCHEMBL17865534	0.81	HRH4 (0.51)	HRH4KMT2AHRH3MEN1RAB9A
	SCHEMBL17865536	0.75	HRH4 (0.53)	HRH4KMT2AHRH3MEN1NPC1
	SCHEMBL17865493	0.75	HRH4 (0.50)	HRH4AKR1C3
	SCHEMBL17865494	0.75	HRH4 (0.50)	HRH4AKR1C3
	SCHEMBL17865666	0.75	PARP14 (0.39)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.