Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 12/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.42 |
| ▸ | CDK2 | P24941 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17865500 | 0.92 | HRH4 (0.51) | HRH4NPC1RAB9AHRH3MEN1 | |
| SCHEMBL16523116 | 0.86 | HRH4 (0.44) | HRH4NPC1RAB9AHRH3MEN1 | |
| SCHEMBL17865549 | 0.85 | HRH4 (0.43) | HRH4NPC1RAB9AHRH3MEN1 | |
| SCHEMBL17865536 | 0.84 | HRH4 (0.53) | HRH4NPC1RAB9AHRH3MEN1 | |
| SCHEMBL17865521 | 0.78 | HRH3 (0.46) | HRH4RAB9AHRH3 | |
| SCHEMBL17865542 | 0.78 | HRH4 (0.54) | HRH4HRH3 | |
| SCHEMBL16523104 | 0.78 | HRH4 (0.54) | HRH4NPC1RAB9AHRH3MEN1 | |
| SCHEMBL17865666 | 0.77 | PARP14 (0.39) | — | |
| SCHEMBL17865504 | 0.76 | PIN1 (0.41) | HRH4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL17865567 | 0.74 | HRH4 (0.51) | HRH4RAB9AHRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3037412-B1 | INDOLE AMIDE COMPOUND AS INHIBITOR OF NECROSIS | LG CHEMICAL LTD (KR) | 2020-09-30 | — | — | EP | disclosed |