SCHEMBL165236

SCHEMBL165236

c1cc(-c2ccsc2-c2ccsc2)cs1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.43
CYP2B6 P20813 2/20 0.43
MAPK14 Q16539 1/20 0.43
CYP2E1 P05181 1/20 0.43
TDO2 P48775 1/20 0.40
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
CES1 P23141 1/20 0.39
PTGS1 P23219 4/20 0.38
USP2 O75604 2/20 0.37
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
ALOX15 P16050 1/20 0.37
KMT2A Q03164 1/20 0.37
HSD17B10 Q99714 1/20 0.37
GPR35 Q9HC97 1/20 0.37
ALDH1A1 P00352 1/20 0.37
PKM P14618 1/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28260577 0.96 CYP2A6 (0.50) CYP2A6CYP2B6MAPK14CYP2E1TDO2
Octane SCHEMBL27651712 0.86 MEN1 (0.40) CYP2A6CYP2B6MAPK14CYP2E1TDO2
Dodecane SCHEMBL27631273 0.86 MEN1 (0.40) CYP2A6CYP2B6MAPK14CYP2E1TDO2
SCHEMBL27651714 0.86 MEN1 (0.40) CYP2A6CYP2B6MAPK14CYP2E1TDO2
SCHEMBL28253950 0.83 CYP2A6 (0.52) CYP2A6CYP2B6MAPK14CYP2E1CYP3A4
SCHEMBL27514810 0.83 GPR35 (0.47) CYP2A6CYP2B6CYP2E1PTGS1USP2
SCHEMBL27705126 0.82 USP2 (0.39) CYP2A6CYP2B6MAPK14CYP2E1TDO2
SCHEMBL27631275 0.82 MEN1 (0.42) CYP2A6CYP2B6MAPK14CYP2E1TDO2
SCHEMBL27705123 0.82 CYP2A6 (0.36) CYP2A6CYP2B6MAPK14CYP2E1TDO2
SCHEMBL27659797 0.82 MAPK14 (0.41) CYP2A6CYP2B6MAPK14CYP2E1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 788 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416167-A1 OSMIUM-CONTAINING CONJUGATED POLYMER AND METHODS THEREOF XIAMEN UNIVERSITY (CN) 2022-12-29 US claimed
CN-114684815-A Method for repairing structural defects of graphene 南通普朗克石墨烯科技有限公司 2022-07-01 CN claimed
WO-2021143690-A1 OSMIUM-CONTAINING CONJUGATED POLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF 厦门大学 2021-07-22 WO claimed
EP-3368197-B1 METHOD FOR MANUFACTURING OF A CARBON NANOMEMBRANE CNM TECH GMBH (DE) 2021-07-14 EP claimed
US-11009802-B2 Pellicle CNM TECHNOLOGIES GMBH (DE) 2021-05-18 US claimed
CN-112745485-A Osmium-containing conjugated polymer and preparation method and application thereof 厦门大学 2021-05-04 CN claimed
CN-112592465-A Osmium-containing heteropentadiyne conjugated polymer with main chain and preparation method and application thereof 厦门大学 2021-04-02 CN claimed
US-20200388836-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH FUNCTIONAL TERTHIOPHENE COMPOUND OR THIOPHENE OLIGOMER COMPOUND CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-12-10 US claimed
US-10646831-B2 Method for manufacturing of a carbon nanomembrane CNM TECHNOLOGIES GMBH (DE) 2020-05-12 US claimed
CN-109004274-B Electrolyte solution and secondary battery 宁德时代新能源科技股份有限公司 2020-04-24 CN claimed
US-20050059730-A1 Thiophene-containing compound and thiophene-containing compound polymer FUJIFILM BUSINESS INNOVATION CORP. (JP) 2005-03-17 US claimed
US-6764758-B1 Surface-modified layer system UNIVERSITAT HEIDELBERG (DE) 2004-07-20 US claimed
EP-1432693-A2 MCH RECEPTOR ANTAGONISTS Taisho Pharmaceutical Co. Ltd. (JP) 2004-06-30 EP claimed
EP-1204714-B1 BI-OR TERTHIENYL SUBSTITUTED PHOTOCHROMIC NAPHTHO 2,1-B]PYRAN COMPOUNDS ESSILOR INT (FR) 2004-01-28 EP claimed
WO-2003028641-A2 MCH RECEPTOR ANTAGONISTS TAISHO PHARMACEUTICAL CO., LTD. (JP) 2003-04-10 WO claimed
EP-1222498-A2 SURFACE-MODIFIED LAYER SYSTEM Universität Heidelberg (DE) 2002-07-17 EP claimed
US-6312811-B1 Photochromic naphtho [2,1-b]pyran compounds containing bithienyl or terthienyl substituents, process for their manufacture, and photochromic materials and articles obtained ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2001-11-06 US claimed
WO-2001023962-A2 SURFACE-MODIFIED LAYER SYSTEM Universität Heidelberg (DE) 2001-04-05 WO claimed
US-5180838-A Terthienyl compounds as insecticides HER MAJESTY THE QUEEN AS REPRESENTED BY THE MINISTER OF NATIONAL DEFENSE OF HER MAJESTY'S CANADIAN GOVERNMENT (CA) 1993-01-19 US claimed
EP-0192492-B1 PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1992-01-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050059730-A1 Thiophene-containing compound and thiophene-containing compound polymer SLCO4C1, SLCO2A1, SLCO2B1 CYP2A6 1215/4885CYP2B6 988/4885MAPK14 2172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.