SCHEMBL1652437

SCHEMBL1652437

C=C[Si](CC)(CC)CC.COC(=O)C1=CCC1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.40
CHRM3 P20309 3/20 0.38
CHRM2 P08172 2/20 0.37
CHRM4 P08173 2/20 0.37
CHRM5 P08912 2/20 0.37
CHRM1 P11229 2/20 0.37
LMNA P02545 1/20 0.37
THRB P10828 1/20 0.37
BLM P54132 1/20 0.36
MCOLN3 Q8TDD5 1/20 0.36
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Vinyl Chloride SCHEMBL2422727 0.80 PTPN1 (0.45) PTPN1CHRM3CHRM2CHRM4CHRM5
SCHEMBL43992 0.79
Acrylic Acid SCHEMBL305444 0.78 PTPN1 (0.48) PTPN1CHRM3CHRM2CHRM4CHRM5
SCHEMBL5857909 0.76 PTPN1 (0.49) PTPN1CHRM3CHRM2CHRM4CHRM5
SCHEMBL15569637 0.74 PTPN1 (0.41) PTPN1CHRM3CHRM2CHRM4CHRM5
Acetic Acid SCHEMBL5156006 0.74 PTPN1 (0.49) PTPN1CHRM3CHRM2CHRM4CHRM5
SCHEMBL7196625 0.73 TSHR (0.59) PTPN1LMNATHRBALDH1A1MAPT
SCHEMBL9182227 0.72 PTPN1 (0.47) PTPN1CHRM3CHRM2CHRM4CHRM5
Styrene SCHEMBL1713925 0.72 ALDH1A1 (0.44) PTPN1CHRM3CHRM2CHRM4CHRM5
SCHEMBL8593973 0.69 CHRM3 (0.38) PTPN1CHRM3CHRM2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312877-A1 NON-HALOGENATED MULTI-MELAMINE FLAME-RETARDANT COMPOUNDS AND SALTS THEREOF AND PROCESSES FOR THEIR PREPARATION STATE OF ISRAEL, PRIME MINISTER'S OFFICE, ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 2023-10-05 US disclosed
EP-4204491-A1 NON-HALOGENATED MULTI-MELAMINE FLAME-RETARDANT COMPOUNDS AND SALTS THEREOF AND PROCESSES FOR THEIR PREPARATION State of Israel Prime Minister's Office Israel Institute for Biological Research (IL) 2023-07-05 EP disclosed
US-9828501-B2 Flame retardant with compositions KASOWSKI ROBERT VALENTINE (US) 2017-11-28 US disclosed
US-20150080486-A1 Flame Retardant with Compositions KASOWSKI ROBERT VALENTINE (US) 2015-03-19 US disclosed
US-8703853-B2 Flame retardant and composition containing it KASOWSKI ROBERT VALENTINE (US) 2014-04-22 US disclosed
US-20130341575-A1 New flame retardant and composition containing it KASOWSKI ROBERT VALENTINE (US) 2013-12-26 US disclosed
EP-1455901-B1 REACTION PRODUCT OF A PHOSPHOROUS ACID WITH ETHYLENEAMINES, FORMALDEHYDE AND AMINE FOR FLAME RESISTANCE KASOWSKI ROBERT VALENTINE (US) 2013-09-25 EP disclosed
WO-2012166210-A1 FLAME RETARDANT WITH COMPOSITIONS KASOWSKI ROBERT VALENTINE (US) 2012-12-06 WO disclosed
US-20120282490-A1 NEW FLAME RETARDANT AND COMPOSITION CONTAINING IT KASOWSKI ROBERT VALENTINE (US) 2012-11-08 US disclosed
US-8212073-B2 Protective barrier composition comprising reaction of phosphorous acid with amines applied to a substrate KASOWSKI ROBERT VALENTINE (US) 2012-07-03 US disclosed
WO-2011049615-A1 NEW FLAME RETARDANT AND COMPOSITON CONTAINING IT KASOWSKI ROBERT VALENTINE (US) 2011-04-28 WO disclosed
US-20090048372-A1 PROTECTIVE BARRIER COMPOSITION COMPRISING REACTION OF PHOSPHOROUS ACID WITH AMINES APPLIED TO A SUBSTRATE KASOWSKI ROBERT VALENTINE 2009-02-19 US disclosed
EP-1745114-A1 PROTECTIVE BARRIER COMPOSITION COMPRISING REACTION OF PHOSPHOROUS ACID WITH AMINES APPLIED TO A SUBSTRATE Kasowski, Robert Valentine (US) 2007-01-24 EP disclosed
US-7138443-B2 Reaction product of a phosphorous acid with ethyleneamines, formaldehyde, and amine for flame resistance KASOWSKI ROBERT VALENTINE 2006-11-21 US disclosed
US-20060175587-A1 Reaction product of a phosphorous acid with ethyleneamines for flame resistance KASOWSKI MAYA M 2006-08-10 US disclosed
WO-2005054408-A1 PROTECTIVE BARRIER COMPOSITION COMPRISING REACTION OF PHOSPHOROUS ACID WITH AMINES APPLIED TO A SUBSTRATE KASOWSKIK ROBERT VALENTINE (US) 2005-06-16 WO disclosed
US-20050029499-A1 Reaction product of a phosphorous acid with ethyleneamines, formaldehyde, and amine for flame resistance KASOWSKI ROBERT VALENTINE (US) 2005-02-10 US disclosed
EP-1455901-A2 REACTION PRODUCT OF A PHOSPHOROUS ACID WITH ETHYLENEAMINES, FORMALDEHYDE, AND AMINE FOR FLAME RESISTANCE Kasowski, Robert Valentine (US) 2004-09-15 EP disclosed
WO-2003049812-A2 REACTION PRODUCT OF A PHOSPHOROUS ACID WITH ETHYLENEAMINES, FORMALDEHYDE, AND AMINE FOR FLAME RESISTANCE KASOWSKI ROBERT VALENTINE (US) 2003-06-19 WO disclosed