SCHEMBL165271

SCHEMBL165271

c1ncc2ncsc2n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29504479 1.00
Urea SCHEMBL1760920 0.88 PI4KA (0.36)
Piperazine SCHEMBL798274 0.88 PI4KA (0.32)
SCHEMBL28957900 0.85 PI4KA (0.31)
Acetamide SCHEMBL9933914 0.85 PI4KA (0.34)
SCHEMBL655393 0.82
SCHEMBL31049795 0.79
SCHEMBL30770352 0.77
SCHEMBL1602375 0.76 EGFR (0.34)
SCHEMBL19118755 0.71 PIK3CG (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2792 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137697-A1 THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF UNIV DE MONTREAL (CA) 2026-05-21 US claimed
EP-4602047-A1 THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF The Universite de Montreal (CA) 2025-08-20 EP claimed
CN-120035595-A Thiazolo [5,4-d ] pyrimidine compounds, compositions comprising the same and uses thereof 蒙特利尔大学 2025-05-23 CN claimed
US-20250072277-A1 LIGHT EMITTING ELEMENT AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2025-02-27 US claimed
CN-119521943-A Light emitting element and display device including the same 三星显示有限公司 2025-02-25 CN claimed
US-20240246959-A1 BENZIMIDAZOLE DERIVATIVE AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD. (CN) 2024-07-25 US claimed
WO-2024077391-A1 THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF UNIVERSITE DE MONTREAL (CA) 2024-04-18 WO claimed
EP-4242202-A1 BENZIMIDAZOLE DERIVATIVE AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF Shenzhen Salubris Pharmaceuticals Co., Ltd. (CN) 2023-09-13 EP claimed
WO-2023109158-A1 7-METHYLTHIAZOLO[5,4-D]PYRIMIDINE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海博悦生物科技有限公司 2023-06-22 WO claimed
US-20230057355-A1 GENE NETWORKS THAT MEDIATE REMYELINATION OF THE HUMAN BRAIN UNIVERSITY OF ROCHESTER 2023-02-23 US claimed
EP-0348746-A2 Thiazolopyrimidine derivatives, process for their preparation and their use as pest control agents BAYER AG (DE) 1990-01-03 EP claimed
EP-0347183-A2 Dye solution and process for the preparation of information recording medium FUJI PHOTO FILM CO., LTD. (JP) 1989-12-20 EP claimed
EP-0101518-B1 THIAZOLOPYRIMIDINE DERIVATIVE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1986-03-12 EP claimed
US-4505840-A Heterocyclic electroactive polymers CHEVRON RESEARCH COMPANY (US) 1985-03-19 US claimed
EP-0101518-A1 THIAZOLOPYRIMIDINE DERIVATIVE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1984-02-29 EP claimed
US-4226863-A BACTERICIDES, ANTIBIOTICS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-10-07 US claimed
US-4160087-A BACTERICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-07-03 US claimed
US-4156724-A N-acylamino-alpha-arylacetamido cephalosporins and antibacterial compositions and methods containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-05-29 US claimed
US-4125611-A MICROBIOCIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1978-11-14 US claimed
US-4005075-A Penicillins and their preparation SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-01-25 US claimed