Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 20/20 | 0.82 |
| ▸ | AVPR1A | P37288 | 20/20 | 0.82 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | OXTR | P30559 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257280 | 1.00 | AVPR2 (0.82) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL255996 | 0.90 | AVPR2 (1.00) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL19244854 | 0.88 | AVPR2 (0.85) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL257278 | 0.88 | AVPR2 (0.80) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL12057196 | 0.88 | AVPR2 (0.79) | AVPR2AVPR1A | |
| SCHEMBL3446749 | 0.86 | AVPR2 (0.78) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL4502013 | 0.84 | AVPR2 (0.76) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL19244869 | 0.83 | AVPR2 (0.74) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL718656 | 0.83 | AVPR2 (0.74) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL414412 | 0.83 | AVPR2 (0.74) | AVPR2AVPR1ASLC6A2OXTROPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619188-A1 | SUBSTITUTED N-PHENETHYLTRIAZOLONEACETAMIDES AND USE THEREOF | Bayer Intellectual Property GmbH (DE) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012028644-A1 | SUBSTITUTED N-PHENETHYLTRIAZOLONEACETAMIDES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-08 | — | — | WO | disclosed |